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Frank Reidy Research Center for Bioelectrics:Publications

2014 Journal Publications

Aggarwal S, Gross CM, Kumar S, Dimitropoulou C, Sharma S, Gorshkov BA, Sridhar S, Lu Q, Bogatcheva NV, Jezierska-Drutel AJ, Lucas R, Verin AD, Catravas JD, Black SM. Dimethylarginine Dimethylaminohydrolase II Overexpression Attenuates LPS-Mediated Lung Leak in Acute Lung Injury. Am J Respir Cell Mol Biol., 50(3):614-25, 2014. [Article Link]
Ali SW, Malik MA, Jan S, Naeem K. Comparison of Rigid Divinylbenzene with Flexible 1,7-Octadiene Crosslinks in Acrylic Acid Resins-Effects on Kinetics of Swelling and Loading of Heavy Metal Ions from Water. J. Appl. Polym. Sci., 131:41038, 2014. [Article Link]
Bao X, Malik MA, Norton DG, Neculaes VB, Schoenbach KH, Heller R, Siclovan OP, Corah SE, Caiafa A, Inzinna LP, Conway, KR. Shielded Sliding Discharge-Assisted Hydrocarbon Selective Catalytic Reduction of NOx over Ag/Al2O3 Catalysts Using Diesel as a Reductant. Plasma Chem. Plasma Process, 34:825-36, 2014. [Article Link]
Basu G, Downey H, Guo S, Israel A, Asmar A, Hargrave B and Heller R. Prevention of distal flap necrosis in a rat random flap model by gene electrotransfer delivering VEGF165 plasmid. J. Gene Medicine, in Press, 2014. [Article Link]
Edelblute C, Donate A, Hargrave B, Heller L. Human platelet gel supernatant inactivates opportunistic wound pathogens on skin. Platelets, in Press, 2014. [Article Link]
Guo F, Yao C, Bajracharya C, Polisetty S, Schoenbach KH, and Xiao S. Simulation Study of Delivery of Subnanosecond Pulses to Biological Tissues With an Impulse Radiating Antenna. Bioelectromagnetics, 35(2):145-59, 2014. [Article Link]
Ibey BL, Ullery JC, Pakhomova ON, Roth CC, Semenov I, Beier HT, Tarango M, Xiao S, Schoenbach KH, Pakhomov AG. Bipolar nanosecond electric pulses are less efficient at electropermeabilization and killing cells than monopolar pulses. Biochem Biophys Res Commun., 443(2):568-73, 2014. [Article Link]
Joshi AD, Dimitropoulou C, Thangjam G, Snead C, Feldman S, Barabutis N, Fulton D, Hou Y, Kumar S, Patel V, Gorshkov B, Verin AD, Black SM, Catravas JD. Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling. Am J Respir Cell Mol Biol., 50(1):170-9, 2014. [Article Link]
Malik MA, Jiang C, Dhali SK, Heller R, & Schoenbach KH. Coupled Sliding Discharges: A Scalable Nonthermal Plasma System Utilizing Positive and Negative Streamers on Opposite Sides of a Dielectric Layer. Plasma Chemistry and Plasma Processing, in Press, 2014. [Article Link]
Malik MA, Schoenbach KH. Nitric oxide conversion and ozone synthesis in a shielded sliding discharge reactor with positive and negative streamers. Plasma Chemistry and Plasma Processing, 34(1):93-109, 2014. [Article Link]
Pakhomov AG, Xiao S, Pakhomova ON, Semenov I, Kuipers MA, Ibey BL. Disassembly of actin structures by nanosecond pulsed electric field is a downstream effect of cell swelling. Bioelectrochemistry, S1567-5394(14)00016-4, 2014. [Article Link]
Rassokhin MA and Pakhomov AG. Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF). Cell Biochem Biophys., in Press, 2014. [Article Link]
Rafikov R, Dimitropoulou C, Aggarwal S, Kangath A, Gross C, Pardo D, Sharma S, Jezierska-Drutel A, Patel V, Snead C, Lucas R, Verin A, Fulton D, Catravas JD, Black SM. Lipopolysaccharide-induced Lung Injury Involves the Nitration-mediated Activation of RhoA. J Biol Chem., 289(8):4710-22, 2014. [Article Link]
Schoenbach KH and Malik MA. Scaling of Shielded Sliding Discharges for Environmental Applications. Plasma Chemistry and Plasma Processing, 34(1):39-54, 2014. [Article Link]
Stacey MW, Sabuncu AC, and Beskok A. Dielectric Characterization of Costal Cartilage Chondrocytes. Biochem Biophys Acta (BBA)-General Subjects, 1840(1):146-52, 2014. [Article Link]

2013 Journal Publications

Ali SW, Waqar F, Malik MA, Yasin T and Muhammad B. Study on the Synthesis of a Macroporous Ethylacrylate-Divinylbenzene Copolymer, Its Conversion Into a Bi-Functional Cation Exchange Resin and Applications for Extraction of Toxic Heavy Metals From Wastewater. J Appl Polym Sci, 129(4):2234-43, 2013. [Article Link]
Barabutis N, Handa V, Dimitropoulou C, Rafikov R, Snead C, Kumar S, Joshi A, Thangjam G, Fulton D, Black SM, Patel V, Catravas JD. LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung. Am J Physiol Lung Cell Mol Physiol., 304(12):L883-93, 2013. [Article Link]
Beebe SJ. Cell Responses without Receptors and Ligands using Nanosecond Pulsed Electric Fields (nsPEFs). Editorial; Intern J Nanomed, 8:3401-4, 2013. [Article Link]
Beebe SJ, Sain NM and Ren W. Induction of Cell Death Mechanisms and Apoptosis by Nanosecond Pulsed Electric Fields (nsPEFs). Cells, 2(1):136-62, 2013. [Article Link]
Beebe SJ. Applications for Pulse Power using Nanosecond Pulsed Electric Fields (nsPEFs) in Cell Biology and Cancer Treatment. Editorial; J of Nanomed and Biotherap Dis, 3:1000e123, 2013. [Article Link]
Chen R, Chen X and Beebe SJ. Nanosecond Pulsed Electric Field (nsPEF) Ablation as an Alternative or Adjunct to Surgery for Treatment of Cancer. Surgery: Current Research, S12:005, 2013.
Cobb D, Guo, S, Smeltz RB. CpG and interleukin-15 synergize to enhance CD8+ T cell function. BioMed Research International, 2013. [Article Link]
Donate A and Heller R. Assessment of delivery parameters with the multi-electrode array for development of a DNA vaccine against Bacillus anthracis. Bioelectrochemistry, 94:1-6, 2013. [Article Link]
Evseev AI, Semenov I, Archer CR, Medina JL, Dube PH, Shapiro MS, Brenner R. Functional effects of KCNQ K(+) channels in airway smooth muscle. Front Physiol., 4:277, 2013. [Article Link]
Guo S, Israel A, Basu G, Donate A and Heller R. Topical gene electrotransfer to the epidermis by non-invasive multielectrode array. PLoS ONE 8(8):e73423, 2013. [Article Link]
Hargrave B, Downey H, Strange R Jr., Murray L, Cinnamond C, Lundberg C, Israel A, Chen Y-J, Marshall W Jr. and Heller R. Electroporation-mediated gene transfer directly to the swine heart. Gene Therapy, 20(2):151-57, 2013. [Article Link]
Heller LC, Todorovic, Vesna, Cemazar M. Electrotransfer of single-stranded or double-stranded DNA induces complete regression of palpable B16.F10 mouse melanomas. Cancer Gene Ther, 20(12):695-700, 2013. [Article Link]
Ho, M.-C., Z. A. Levine, and P. T. Vernier. Nanoscale, electric field-driven water bridges in vacuum gaps and lipid bilayers. J. Membrane Biol., 246(11):793-801, 2013. [Article Link]
Ho MC, Casciola M, Levine ZA, and Vernier PT. Molecular dynamics simulations of ion conductance in field-stabilized nanoscale lipid electropores. J. Phys. Chem. B, 117(39):11633-40, 2013. [Article Link]
Joshi SK, Lang ML. Fine tuning a well-oiled machine: Influence of NK1.1 and NKG2D on NKT cell development and function. Int Immunopharmacol, 17(2):260-6, 2013. [Article Link]
Malik MA, Schoenbach KH. Sliding discharges in steam: effects of dielectric surface and hydrocarbon additives on hydrogen, oxygen and hydrogen peroxide generation. J. Phys. D: Appl. Phys., 46:145201, 2013. [Article Link]
Malik MA, Ali SW, Ahmed I. Economical and environmentally friendly synthesis of porous cation-exchange resins. SPE Plastics Research Online, 2013. [Article Link]
Malik MA, Hughes D, Malik A, Xiao S, Schoenbach KH. Study of the Production of Hydrogen and Light Hydrocarbons by Spark Discharges in Diesel, Kerosene, Gasoline, and Methane. Plasma Chem Plasma Process, 33(1):271-9, 2013. [Article Link]
Marrero B, Shirley S and Heller R. Delivery of interleukin-15 to B16 melanoma by electroporation leads to tumor regression and long term survival. TCRT August 31, Epub ahead of print, 2013. [Article Link]
Pakhomov AG. Response to "Sodium current inhibition by nanosecond pulsed electric field (nsPEF)-fact or artifact?" by Verkerk et al. Bioelectromagnetics, 34(2):165-6, 2013. [Article Link]
Pakhomova ON, Gregory BW, Semenov Iu, and Pakhomov AG. Two modes of cell death caused by exposure to nanosecond pulsed electric field. PLOS One, 8(7):e70278, 2013. [Article Link]
Pakhomova ON, Gregory BW, and Pakhomov AG. Facilitation of the electroporative drug uptake and cell killing by electrosensitization. J Cell Mol Med., 17(1):154-9, 2013. [Article Link]
Romeo S, Wu Y-H, Levine ZA, Gundersen MA, and Vernier PT. Water influx and cell swelling after nanosecond electropermeabilization. Biochim. Biophys. Acta., 1828(8):1715-22, 2013. [Article Link]
Schaudinn C, Jaramillo DE, Freire M, Sedghizadeh PP, Nguyen A, Webster P, Costerton JW, and Jiang C. Evaluation of a non-thermal plasma needle to eliminate ex vivo
biofilms in root canals of extracted human teeth. International Endodontic Journal, 46(10):930-937, 2013. [Article Link]
Semenov Iu, Xiao S, and Pakhomov AG. Primary pathways of intracellular Ca(2+) mobilization by nanosecond pulsed electric field. Biochim Biophys Acta., 1828(3):981-9, 2013. [Article Link]
Semenov Iu, Xiao S, Pakhomova ON, and Pakhomov AG. Recruitment of the intracellular Ca2+ by ultrashort electric stimuli: the impact of pulse duration. Cell Calcium, 54(3):145-50, 2013. [Article Link]
Shah HB, Joshi SK, Rampuria P, Devera TS, Lang GA, Stohl W, Lang ML. BAFF- and APRIL-dependent maintenance of antibody titers after immunization with T-dependent antigen and CD1d-binding ligand. J Immunol., 191(3):1154-63, 2013. [Article Link]
Stacey M, Dutta D, Cao W, Asmar A, El-Sayed Ali H, Kelly Jr R, Beskok A. Atomic Force Microscopy Characterization of Collagen 'Nanostraws' in Human Costal Cartilage. Micron 44:483-87, 2013. [Article Link]
Thangjam GS, Dimitropoulou C, Joshi AD, Barabutis N, Shaw MC, Kovalenkov Y, Wallace CM, Fulton DJ, Patel V, Catravas JD. Novel Mechanism of Attenuation of LPS-Induced NF-ĸB Activation by the hsp90 Inhibitor, 17-AAG, in Human Lung Microvascular Endothelial Cells. Am J Respir Cell Mol Biol., In Press , 2013. [Article Link]
Tokman M, Lee JH, Levine ZA, Ho M-C, Colvin ME, and Vernier PT. Electric field-driven water dipoles: nanoscale architecture of electroporation. PLoS ONE, 8(4):e61111, 2013. [Article Link]
Vernier PT, Levine ZA and Gundersen MA. Water bridges in electropermeabilized phospholipid bilayers. Proc. IEEE, 101(2):494-504, 2013. [Article Link]
Wu Y-H, Arnaud-Cormos D, Casciola M, Sanders JM, Leveque P, and Vernier PT. Moveable wire electrode microchamber for nanosecond pulsed electric field delivery. IEEE Trans. Biomed. Eng., 60(2):489-96, 2013. [Article Link]

2012 Journal Publications

Ali SW, Malik MA, Ahmed I. Synthesis of Strong Acid Resins From Macroporous Styrene-Divinylbenzene Copolymers: Is Diluent Extraction Step Necessary? Polym. Eng. Sci., 52(11):2375-82, 2012. [Article Link]
Beebe SJ. Bioelectrics in Basic Science and Medicine: Impact of Electric Fields on Cellular Structures and Functions. J Nanomedic Nanotechnol, 4:163, 2012. [Article Link]
Beebe SJ, Chen Y-J, Sain NM, Schoenbach KH, and Xiao S. Transient Features in Nanosecond Pulsed Electric Fields Differentially Modulate Mitochondria and Viability. PLoS One; 7(12): e51349, 2012. [Article Link]
Camp JT, Jing Y, Zhuang J, Kolb J, Beebe SJ, Song J, Joshi RP, Xiao S and Schoenbach KH. Cell Death Induced by Subnanosecond Pulsed Electric Fields at Elevated Temperatures. IEEE Trans. Plasma Science, 40(10):2334-47, 2012. [Article Link]
Chen XH, Beebe SJ and Zheng SS. Tumor ablation with nanosecond pulsed electric fields. Hepatobiliary Pancreat Dis Int, 11(2):122-4, 2012. [Article Link]
Chen X, Zhuang J, Kolb JF, Schoenbach KH and Beebe SJ. Long Term Survival of Mice With Hepatocellular Carcinoma after Pulse Power Ablation with Nanosecond Pulsed Electric Fields. Technol Cancer Res Treat, 11(1):83-93, 2012. [Article Link]
Craviso G L, Choe S, Chatterjee I and Vernier PT. Modulation of intracellular Ca2+ levels in chromaffin cells by nanoelectropulses. Bioelectrochemistry 87:244-52, 2012. [Article Link]
Denning W, Das S, Guo S, Xu J, Kappes JC, Hel Z. Optimization of the Transductional Efficiency of Lentiviral Vectors: Effect of Sera and Polycations. Mol Biotechnol., 53(3):308-14, 2012. [Article Link]
DeSantiago J, Bare DJ, Semenov I, Geenen D, Wolska B and Banach K. Excitation-Contraction Coupling in Ventricular Myocytes is Enhanced by Paracrine Signalling from Mesenhimal Stem Cells. J Mol Cell Cardiol., 52(6):1249-56, 2012. [Article Link]
Deutsch S, Urbano MR and Zemlin C. Mouse models have limitations for development of medications for autism spectrum disorders, but also show much promise. Future Neurology, 7(1):1-4, 2012. [Article Link]
Fernandez ML, Risk M, Reigada R, and Vernier PT. Size-controlled nanopores in lipid membranes with stabilizing electric fields. Biochemical and Biophysical Research Communications 423(2):325-30, 2012. [Article Link]
Gruslova A, Semenov I, Wang B. An extracellular domain of the accessory ß1 subunit is required for modulating BK channel voltage sensor and gate. J Gen Physiol., 139(1):57-67, 2012. [Article Link]
Hargrave, B. & Li, F. Nanosecond pulse electric field activation of platelet-rich plasma reduces myocardial infarct size and improves left ventricular mechanical function in the rabbit heart. JECT, 44(4):198-204, 2012. [Article Link]
Heller LC, Edelblute CM, Mattson AM, Hao X, Singh T, Kolb JK. Inactivation of bacterial opportunistic skin pathogens by nonthermal DC-operated afterglow atmospheric plasma. Letters in Applied Micro 54(2):126-32, 2012. [Article Link]
Horth L, Stacey MW, Benjamin T, Segna K, Proud VK, Nuss D, Kelly RE. Advancing our understanding of the inheritance and transmission of pectus excavatum. J. Pediatric Genet., 1(3):161-73, 2012. [Article Link]
Jan S, Waqar F, Ali SW, Malik MA, Mohammad B, Khan M and Yawar W. Synthesis and application of a bifunctional sorbent derived from ethylacrylate-divinylbenzene copolymer for the solid-phase extraction of pesticides from water. Journal of Liquid Chromatography & Related Technologies, 35(5):700-11, 2012. [Article Link]
Jiang C, Schaudinn C, Jaramillo DE, Webster P, and Costerton JW. In vitro
antimicrobial effect of a cold plasma jet against enterococcus faecalis biofilms. ISRNDentistry,
2012:295736, 2012. [Article Link]
Joshi SK, Lang GA, Devera TS, Johnson AM, Kovats S, Lang ML. Differential contribution of dendritic cell CD1d to NKT cell-enhanced humoral immunity and CD8+ T cell activation. J Leukoc Biol., 91(5):783-90, 2012. [Article Link]
Kalluri BS, Basu G, Osgood CJ and Stacey MW. Enhanced killing effect of Nanosecond Pulse Electric Fields (nsPEFs) on PANC1 and Jurkat cell lines in the presence of Tween 80. J. Membrane Biology, 245(10):611-16, 2012. [Article Link]
Kolb JF, Mattson AM, Edelblute CM, Hao X, Price RO, Singh TJ, Malik MA and Heller LC. Cold DC Operated Air Plasma Jet for the Inactivation of Infectious Microorganisms. IEEE Transactions on Plasma Science, 40(11):3007-26, 2012. [Article Link]
Levine ZA and Vernier PT. Calcium and phosphatidylserine inhibit lipid electropore formation and reduce pore lifetime. J. Membrane Biol. 245(10):599-610, 2012. [Article Link]
Malik MA, Xiao S, Schoenbach KH. Scaling of surface-plasma reactors with a significantly increased energy density for NO conversion. J. Hazard mater, 30:209- 10, 2012. [Article Link]
Malik MA, Schoenbach KH. New approach for sustaining energetic, efficient and scalable non-equilibrium plasma in water vapours at atmospheric pressure. J. Phys. D: Appl. Phys., 45:132001, 2012. [Article Link]
Marrero B and Heller R. The use of an in vitro 3D melanoma model to predict in vivo plasmid transfection using electroporation. Biomaterials, 33(10):3036-46, 2012. [Article Link]
Napotnik TB, Wu Y-H, Gundersen MA, Miklavcic D and Vernier PT. Nanosecond electric pulses cause mitochondrial membrane permeabilization in Jurkat cells. Bioelectromagnetics 33(3):257-64, 2012. [Article Link]
Nesin V and Pakhomov AG. Inhibition of voltage-gated Na+ current by nanosecond pulsed electric field (nsPEF) is not mediated by Na+ influx or Ca2+ signaling. Bioelectromagnetics, 33(6):443-51, 2012. [Article Link]
Nesin V, Bowman AM, Xiao S, and Pakhomov AG. Cell permeabilization and inhibition of voltage-gated Ca2+ and Na+ channel currents by nanosecond pulsed electric field (nsPEF). Bioelectromagnetics, 33(5):394-404, 2012. [Article Link]
Pakhomova ON, Khorokhorina VA, Bowman AM, Rodaitė-Riševičienė R, Saulis G, Xiao S, and Pakhomov AG. Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media. Arch Biochem Biophys., 527(1):55-64, 2012. [Article Link]
Rassokhin MA and Pakhomov AG. Electric field exposure triggers and guides formation of pseudopod-like blebs in U937 monocytes. J Membr Biol., 245(9):521-9, 2012. [Article Link]
Ren W, Sain NM and Beebe SJ. Nanosecond pulsed electric fields (nsPEFs) activate intrinsic caspase-dependent and caspase-independent cell death in Jurkat cells. Biochem Biophys Res Commun, 421(4):808-12, 2012. [Article Link]
Sabuncu AC, Grubbs J, Qian S, Abdel-Fattah TM, Stacey MW, Beskok A. Probing nanoparticle interactions in cell culture media. Colloids and Surfaces B: Biointerfaces, 95:96-102, 2012. [Article Link]
Schoenbach KH and Zhu WD. High-Pressure Microdischarges - Sources of Ultraviolet Radiation. Invited Review Paper, IEEE Journal of Quantum Electronics, 48(6):768-82, 2012. [Article Link]
Sedghizadeh PP, Chen MT, Schaudinn C, Gorur A, and Jiang C. Inactivation
Kinetics Study of an Atmospheric-Pressure Cold Plasma Jet against Pathogenic
Microorganisms. IEEE Transactions on Plasma Science, 40(11):2879-82, 2012. [Article Link]
Semenov I, Herlihy J, Brenner R. In vitro measurements of tracheal constriction in mice. J Vis Exp., (64), 2012. [Article Link]
Sozer E, Gundersen MA, and Jiang C. Magnesium Based Photocathodes for Back-
Lighted Thyratrons. IEEE Transaction on Plasma Science, 40(6):1753-58, 2012. [Article Link]
Stacey MW, Grubb J, Asmar A, Pryor J, Elsayed-Ali H, Cao W, Beskok A, Dutta D, Darby DA, Fecteau A, Werner A, Kelly RE Jr. Decorin Expression, Straw-like Structure, and Differentiation of Human Costal Cartilage. Connective Tissue Research, 53(5):415-21, 2012. [Article Link]
Wang J, Guo J, Wu S, Feng H, Sun S, Pan J, Zhang J and Beebe SJ. Synergistic effects of nanosecond pulsed electric fields combined with low concentration of gemcitabine on human oral squamous cell carcinoma in vitro. PLoS One, 7(8):e43213, 2012. [Article Link]
Yin D, Yang WG, Weissberg J, Goff WB, Chen W, Kuwayama Y, Leiter A, Xing A, Meixel A, Gaut D, Kirkbir F, Sawcer D, Vernier PT, Said JW, Gundersen MA, and Koeffler HP. Cutaneous papilloma and squamous cell carcinoma therapy utilizing nanosecond pulsed electric fields (nsPEF). PLoS ONE, 7(8):e43891, 2012. [Article Link]
Zemlin CW and Pertsov AM. Anchoring of drifting spiral and scroll waves in excitable media. Phys Rev Lett, 109(3):038303, 2012. [Article Link]
Zhang C, Vernier PT, Wu Y-H, and Yang W. Surface chemical immobilization of parylene C with thermosensitive block copolymer brushes based on N-isopropylacrylamide and N-tert-butylacrylamide: Synthesis, characterization, and cell adhesion/detachment. J. Biomed. Mater. Res. B 100(1):217-29, 2012. [Article Link]

2011 Journal Publications

Arnaud-Cormos D, Leveque P, Wu Y-H, Sanders JM, Gundersen MA, and Vernier PT. Microchamber setup characterization for nanosecond pulsed electric field exposure. IEEE Trans. Biomed. Eng. 58(6):1656-62, 2011. [Article Link]
Bajracharya C, Xiao S, Baum CE, and Schoenbach KH. Target Detection with Impulse Radiating Antenna. IEEE Antennas and Wireless Propagation Letters, 10:496-99 , 2011. [Article Link]
Denning W, Xu J, Guo S, Hel Z. Limited transplantation of antigen-expressing hematopoietic stem cells induces long-lasting cytotoxic T cell responses. PLoS One., 6(2):e16897, 2011. [Article Link]
Devera TS, Joshi SK, Aye LM, Lang GA, Ballard JD, Lang ML. Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFNγ. PLoS One, 6(8):e23817, 2011. [Article Link]
Donate A, Coppola D, Cruz Y and Heller R. Evaluation of a novel non-penetrating electrode for use in DNA vaccination. Plos One, 6(4):e19181, 2011. [Article Link]
Ferraro B, Cruz YL, Baldwin M, Coppola D and Heller R. Evaluation of delivery conditions for cutaneous delivery of plasmid DNA by electroporation using a multielectrode array. Gene Therapy, 18(5):496-500, 2011. [Article Link]
Gilbert RA, Llewellyn JA, Schoenbach KH, Heller LC, Hoff AM. Exploring Tissue Response to Field Mediated Plasmid Delivery. ECS Transactions 35(7):145-55, 2011. [Article Link]
Guo S, Donate A, Basu G, Lundberg C, Heller L, Heller R. Characterization of gene electrodelivery to skin using a noninvasive multielectrode array. J Control Release, 151(3):256-62, 2011. [Article Link]
Ibey BL, Roth CC, Pakhomov AG, Bernhard JA, Wilmink GJ, and Pakhomova ON. Dose-dependent Thresholds of 10 ns Electric Pulse Induced Plasma Membrane Disruption and Cytotoxicity in Multiple Cell Lines. PLoS One, 6(1):e15642, 2011. [Article Link]
Joshi RP and Q Hu. Case for applying subnanosecond high-intensity, electrical pulses to biological cells. IEEE Trans. Biomedical Engineering 58(10):2860-6, 2011. [Article Link]
Lang GA, Johnson AM, Devera TS, Joshi SK, Lang ML. Reduction of CD1d expression in vivo minimally affects NKT-enhanced antibody production but boosts B-cell memory. Int Immunol., 23(4):251-60, 2011. [Article Link]
Long G, Shires P, Plescia D, Beebe SJ, Kolb JF, and Schoenbach KH. Targeted Tissue Ablation with Nanosecond Pulses. IEEE Transactions on Biomedical Engineering 58(8):, 2011. [Article Link]
Malik MA and Schoenbach KH. A novel pulsed corona discharge reactor based on surface streamers for NO conversion from N2-O2 mixture gases. Int. J. Plasma & Environ. Sci. Technol., 5(1):50-7, 2011. [Article Link]
Malik MA, Kolb JF, Sun Y, Schoenbach KH. Comparative study of NO removal in surface-plasma and volume-plasma reactors based on pulsed corona discharges. J Hazard Mater, 197:220- 8, 2011. [Article Link]
Malik MA, Kolb JF, Schoenbach KH. Streamers in Water and Along the Insulator Surface in a Wire-Cylinder Gap. IEEE Trans Plasma Sci, 39(11):2626-7, 2011. [Article Link]
Nesin OM, Pakhomova ON, Xiao S, and Pakhomov AG. Manipulation of cell volume and membrane pore comparison following single cell permeabilization with 60- and 600-ns electric pulses. Biochimica et Biophysica Acta - Biomembranes, 1808(3):792-801, 2011. [Article Link]
Pakhomova ON, Gregory BW, Khorokhorina VA, Bowman AM, Xiao S, and Pakhomov AG. Electroporation-induced electrosensitization. PLoS One, 6(2):e17100, 2011. [Article Link]
Ren W and Beebe SJ. An apoptosis targeted stimulus with nanosecond pulsed electric fields (nsPEFs) in E4 squamous cell carcinoma. Apoptosis, 16(4):382-93, 2011. [Article Link]
Romeo S, Zeni L, Sarti M, Sannino A, Scarfì MR, Vernier PT, and Zeni O. DNA electrophoretic migration patterns change after exposure of Jurkat cells to single intense nanosecond electric pulse. PLoS ONE, 6(12):e28419, 2011. [Article Link]
Semenov I, Wang B, Herlihy J, Brenner R. BK Channel beta1 Subunits Regulate Airway Contraction Secondary to M2 Muscarinic Acetylcholine Receptor Mediated Depolarization. J Physiol., 589(Pt 7):1803-17, 2011. [Article Link]
Shah HB, Joshi SK, Lang ML. CD40L-null NKT cells provide B cell help for specific antibody responses. Vaccine, 29(49):9132-36, 2011. [Article Link]
Stacey M, Fox P, Buescher S, Kolb J. Nanosecond pulsed electric field induced cytoskeleton, nuclear membrane and telomere damage adversely impact cell survival. Bioelectrochemistry 82(2):131-4, 2011. [Article Link]
Stacey MW, Osgood CJ, Kalluri BS, Cao W, Elsayed-Ali H and Abdel-Fattah T. Nanosecond Pulse Electric Fields Used in Conjunction with Multi-Wall Carbon Nanotubes (MWCNTs) as a Potential Tumor Treatment. BioMedical Materials, 6(1):011002, 2011. [Article Link]
Song J, Joshi RP, and Schoenbach KH. Synergistic Effects of Local Temperature Enhancements on Cellular Responses in the Context of High-Intensity, Ultrashort Electric Pulses. Med. Biol. Eng. Comput. 49(6):713-8, 2011. [Article Link]
White JA, Pliquett U, Blackmore PF, Joshi RP, Schoenbach KH, and Kolb JF. Plasma Membrane Charging of Jurkat Cells by Nanosecond Pulsed Electric Fields. European Biophysics Journal 40(8):947-57, 2011. [Article Link]
Xiao S, Guo SQ, Nesin V, Heller R, and Schoenbach KH. Subnanosecond Electric Pulses Cause Membrane Permeabilization and Cell Death. IEEE Trans. Biomedical Engineering, Vol. 58(5):1239-45, 2011. [Article Link]
Yang W, Wu Y-H, Yin D, Koeffler HP, Sawcer DE, Vernier PT, and Gundersen MA. Differential sensitivities of malignant and normal skin cells to nanosecond pulsed electric fields. Technology in Cancer Research and Treatment, 10(3):281-86, 2011. [Article Link]
Yang L, Nyalwidhe JO, Guo S, Drake RR, and Semmes OJ. Targeted identification of metastasis-associated cell-surface sialoglycoproteins in prostate cancer. Mol Cell Proteomics., 10(6):M110.007294, 2011. [Article Link]

2010 Journal Publications

Andre FM, Rassokhin MA, Bowman AM, Pakhomov AG. Gadolinium blocks membrane permeabilization by nanoelectropulses and reduces cell death. Bioelectrochemistry 79(1):95-100, 2010. [Article Link]
Baldwin WH, Gregory BW, Osgood CJ, Schoenbach KH, and Kolb JF. Membrane Permeability and Cell Survival after Nanosecond Pulsed Electric Field Exposure - Significance of Exposure Media Composition. IEEE Trans. Plasma Science, 38(10):2948-53, 2010. [Article Link]
Beebe SJ, Ford WE, Ren W, Chen X, and Schoenbach KH. Non-Ionizing Radiation with Nanosecond Pulsed Electric Fields as a Cancer Treatment: In Vitro Studies. Conf Proc IEEE Eng Med Biol 2009:6509-12 , 2010. [Article Link]
Beebe SJ, Schoenbach KH, and Heller R. Bioelectric Applications for Treatment of Melanoma. Review, Cancers, 2(3):1731-70, 2010. [Article Link]
Bowman AM, Nesin ON, Pakhomova ON, Pakhomov AG. Analysis of plasma membrane integrity by fluorescent detection of Tl(+) uptake. J. Membrane Biol., 236(1):15-26, 2010. [Article Link]
Caldwell B, Mitrea B, Pertsov AM, and Zemlin CW. Probing field-induced tissue polarization using fluorescent imaging. Biophys J, 99(7):2056-88, 2010. [Article Link]
Charles E, Joshi SK, Ash JD, Fox BA, Farris AD, Bzik DJ, Lang ML, Blader IJ. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect Immun., 78(8):3484-92, 2010. [Article Link]
Chen X, Kolb J, Swanson R, Schoenbach K, Beebe SJ. Apoptosis Initiation and Angiogenesis Inhibition: Melanoma Targets for Nanosecond Pulsed Electric Fields. Pigment Cell & Melanoma Research, 23(4):554-63 (2010). [Article Link]
Chen X, Chen X, Swanson JR, Schoenbach KH, Yin S, Zheng S. Histopathological Follow-up by Tissue Micro-array in the Survival Study after Melanoma Treated by Nanosecond Pulsed Electric Field (nsPEF). Journal of Dermatological Treatment, 22(3):153-61, 2010. [Article Link]
Craviso GL, Choe S, Chatterjee P, Chatterjee I, and Vernier PT. Nanosecond electric pulses: a novel stimulus for triggering Ca2+ influx into chromaffin cells via voltage-gated Ca2+ channels. Cell. Mol. Neurobiol., 30(8):1259-65, 2010. [Article Link]
Devera TS, Aye LM, Lang GA, Joshi SK, Ballard JD, Lang ML. CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun., 78(4):1610-17, 2010. [Article Link]
Ferraro B, Cruz YL, Baldwin M, Coppola D and Heller R. Increased perfusion and angiogenesis in a hindlimb ischemia model with plasmid FGF-2 delivered by non-invasive electroporation. Gene Therapy, 17(6):763-69, 2010. [Article Link]
Ferraro B, Heller LC, Cruz YL, Guo S, Donate A, Heller R. Evaluation of delivery conditions for cutaneous plasmid electrotransfer using a multielectrode array. Gene Ther, 18(5):496-500, 2010. [Article Link]
Ford WE, Blackmore PF, Schoenbach KH, and Beebe SJ. Nanosecond pulsed electric fields stimulate apoptosis without release of pro-apoptotic factors from mitochondria in B16f10 melanoma. Arch. Biochem. Biophys., 497(1-2):82-89, 2010. [Article Link]
Heller LC, Cruz YL, Ferraro B, Yang H, Heller R. Plasmid injection and application of electric pulses alter endogenous mRNA and protein expression in B16.F10 mouse melanomas. Cancer Gene Ther, 17(12):864-871, 2010. [Article Link]
Heller LC and Heller R. Electroporation Gene Therapy Preclinical and Clinical Trials for Melanoma. Curr Gene Ther, 10(4):312-7, 2010. [Article Link]
Heller R, Cruz Y, Heller LC, Gilbert R and Jaroszeski MJ. Electrically Mediated Delivery of Plasmid DNA to the Skin Using a Multi Electrode Array. Human Gene Therapy, 21(3):357-62, 2010. [Article Link]
Hu Q and Joshi RP. Model Evaluation of Changes in Electrorotation Spectra of Biological Cells After nsPEF Electroporation. IEEE Trans. Dielectr. Electr. Insulation, 17(6):1888-94, 2010. [Article Link]
Ibey BL, Pakhomov AG, Gregory BW, Khorokhorina VA, Roth CC, Rassokhin MA., Bernhard JA, Wilmink GJ, and Pakhomova ON. Selective cytotoxicity of intense nanosecond-duration electric pulses in mammalian cells. Biochimica et Biophysica Acta - General Subjects, 1800(11):1210-19, 2010. [Article Link]
Ibey BL, Payne JA, Mixon D, Bowman AM, Sickendick KA, Wilmink GJ, Roach WP, and Pakhomov AG. Plasma membrane permeabilization by trains of ultra-short electric pulses. Bioelectrochemistry, 79(1):114-21, 2010. [Article Link]
Joshi RP and Schoenbach KH. Bioelectric Effects of Intense, Ultrashort Electric Pulses. Critical Reviews in Bio-Medical Engineering, 38(3):255-304, 2010. [Article Link]
Joshi RP and Song J. Model analysis of electric fields induced by high-voltage pulsing in cylindrical nerves. IEEE Trans. Plasma Science 38(10):2894-2900, 2010. [Article Link]
Joshi RP and Hu Q. Analysis of Cell Membrane Permeabilization Mechanics and Pore Shape Due to Ultrashort Electrical Pulsing. Medical and Biological Engineering and Computing, 48(9):837-44, 2010. [Article Link]
Joshi RP, Mishra A, Xiao S, and Pakhomov AG. Model study of time-dependent muscle response to pulsed electrical stimulation. Bioelectromagnetics, 31(5):361-70, 2010. [Article Link]
Knecht V, Levine ZA, and Vernier PT. Electrophoresis of uncharged oil in water. J. Colloid Interface Sci., 352(2):223-31, 2010. [Article Link]
Kumar P, Baum CE, Altunc S, Buchenauer J, Xiao S, Christodoulou CG, Schamiloglu E, and Schoenbach KH. A Hyperband Antenna to Launch and Focus Fast, High-Voltage Pulses onto Biological Targets. IEEE Trans. Microwave Theory and Techniques, 59(4):1090-1101 , 2010. [Article Link]
Levine ZA and Vernier PT. Life cycle of an electropore: field-dependent and field-independent steps in pore creation and annihilation. J. Membrane Biol., 236(1):27-36, 2010. [Article Link]
Lin X, Gemel J, Glass A, Zemlin CW, Taffet SM, Beyer EC, and Veenstra R. Connexin40 and Connexin43 Determine Gating Properties of Atrial Gap Junction Channels. J Mol Cell Cardiol, 48(1):238-45, 2010. [Article Link]
Malik MA. Water Purification by Plasmas: Which Reactors are Most Energy Efficient? Plasma Chem Plasma Process, 30(1):21-31, 2010. [Article Link]
Malik MA, Ali SW, Ahmed I. Sulfonated Styrene-Divinybenzene Resins: Optimizing Synthesis and Estimating Characteristics of the Base Copolymers and the Resins. Ind. Eng. Chem. Res., 49(6):2608-12, 2010. [Article Link]
Marshall WG Jr., Boone BA, Burgos JD, Gografe SI, Baldwin MK, Danielson ML, Larson MJ, Caretto DR, Cruz Y, Ferraro B, Heller LC, Ugen KE, Jaroszeski MJ, Heller R. Electroporation Mediated Delivery of a Naked DNA Plasmid Expressing VEGF to the Porcine Heart Enhances Protein Expression. Gene Ther, 17(3):419-23, 2010. [Article Link]
Mohamed A-AH, Kolb JF, and Schoenbach KH. Low Temperature, Atmospheric Pressure, Direct Current Microplasma Jet Operated in Air, Nitrogen and Oxygen. European Physical Journal D, 60(3):517-22, 2010. [Article Link]
Muthumani, K, Lambert VM, Kawalekar O, Heller R, Kim JJ, Weiner DB and Ugen KE. Anti-cancer activity of the HIV accessory molecule viral protein R (Vpr): Delivery as a DNA expression plasmid or biologically active peptides. Vaccine, 28(8):2005-10, 2010. [Article Link]
Pakhomova ON, Taylor AB, Holloway SP, Kannan TR, Baseman JB, and Hart PJ. Crystallization and preliminary X-ray analysis of community acquired respiratory distress syndrome toxin from Mycoplasma pneumoniae. Acta Cryst., 66(3):294-96, 2010. [Article Link]
Sabuncu AC, Kalluri BS, Qian S, Stacey MW, Beskok A. Dispersion state and toxicity of mwCNTs in cell culture medium with different T80 concentrations. Colloids and Surfaces B: Biointerfaces, 78(1):36-43, 2010. [Article Link]
Sabuncu A, Liu J, Beebe SJ and Beskok A. Dielectrophoretic separation of melanoma clones. Biomicrofluidics, 4(2):021101, 2010. [Article Link]
Schoenbach KH, Baum CE, Joshi RP, and Beebe SJ. A Scaling Law for Membrane Permeabilization with Nanopulses. Special Issue on Bioelectrics in the IEEE Trans. Dielectrics and Electrical Insulation, 16(5):1224-35, 2010. [Article Link]
Song J, Joshi RP and Beebe SJ. Cellular Apoptosis by Nanosecond, High-Intensity Electric Pulses: Model Evaluation of the Pulsing Threshold and Extrinsic Pathway. Bioelectrochemistry, 79(2):179-86, 2010. [Article Link]
Stacey M, Neumann S, Dooley A, Segna K, Kelly R, Nuss D, Kuhn A, Goretsky M, Fecteau A, Pastor A, Proud V. Variable Number of Tandem Repeat Polymorphisms (VNTRs) in the ACAN Gene Associated with Pectus Excavatum. Clinical Genet, 78(5):502-4 [Article Link]
Wellner M, Zemlin CW and Pertsov AM. Frustrated drift of an anchored scroll wave and the geodesic principle. Phys Rev E., 82(3 pt 2):036122, 2010. [Article Link]
Xiao S, Altunc S, Kumar P, Baum CE, and Schoenbach KH. A Reflector Antenna for Focusing in the Near Field. IEEE Antennas and Wireless Propagation Letters, 9:12-15, 2010. [Article Link]

Books and Book Chapters


Bigey P, Heller R and Scherman D. Electrotrasnfer/Electroproation for Non-Viral Nucleic Acid Delivery. "Gene Transfer, Gene Therapy and Genetic Pharmacology", edited by Daniel Scherman, Imperial College Press, 2014.
Stacey M. Biochemical and histological differences between costal and articular cartilage. In: "Chest Wall Deformities", edited by Amulya K. Saxena., Springer Verlag, in Press, 2014.


Herlihy JT, Semenov I, Brenner R. Assessment of airway hyperresponsiveness in murine tracheal rings. "Mouse Models of Allergic Disease", edited by Allen Irving, Methods Mol Biol., Humana Press, 2013; 1032:257-69.
Jiang C. Emerging applications of plasmas in medicine: fashion vs. efficacy. "Low Temperature Plasma Technology: Methods and Applications", Eds. P. K. Chu
and X. Lu, Taylor & Francis Group, CRC Press. 2013.
Schoenbach KH. Atmospheric Pressure Microcavity Plasmas. In: "Low Temperature Plasma Technology - Methods and Applications", by Paul K. Chu and XinPei Lu, eds., Taylor and Francis Books, Inc. 2013.
Shirley S, Heller L, Heller R. Gene Electrotransfer, "Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition", edited by Templeton, N.S., 2013.


Jiang C, Schaudinn C, Jaramillo DE, Gundersen MA, and Costerton JW. A submicrosecond
pulsed plasma jet for endodontic biofilm disinfection. "Plasma for Bio-Decontamination, Medicine and Food Security, NATO Science for Peace and Security Series A: Chemistry and Biology", eds. Z. Machala et al., Springer Science + Business Media B.V., 2012.
Kolb JF and Stacey M. Subcellular Biological Effects of Nanosecond Pulsed Electric Fields. In: "Plasma for Bio-decontamination, Medicine and Food Security", edited by Zdenko Machala, NATO Science for Peace and Security Series, Springer Publishing, 2012.
Shirley SA, Heller R, and Heller LC. Electroporation Gene Therapy, "Gene Therapy of Cancer, Third Edition", edited by Lattime, E.C. and Gerson, S. L., 2012.


Beebe SJ, Ford WE, Ren W, Chen X. Pulse Power Ablation of Melanoma with Nanosecond Pulsed Electric Fields, In: (Ed.) R. Morton, Treatment of Metastatic Melanoma, In Tech Croatia, 2011, pp. 231-268. ISBN 978-953-307-574-7
Heller LC, and Heller R. Gene electrotransfer to tumor. in Clinical Aspects of Electroporation (S.T. Kee, J. Gehl and E.W. Lee, Eds.) pps. 159-164, Springer, 2011
Joshi RP and Schoenbach KH, "Electric Fields in Biological Cell and Membranes," invited Chapter in Book titled "Electromagnetic Fields in Biological Systems," CRC Press, 2011 [ISBN: 9781439859995].
Pakhomov AG. Practical Guide to High-Resolution Thermometry and Microdosimetry in Pulsed Electromagnetic Fields. In: Radiofrequency Radiation Dosimetry Handbook, 2010 (in press)


Heller LC, and Heller R. Translation of electroporation-mediated DNA delivery to the clinic. in Advance Electroporation Techniques in Biology and Medicine (A.G. Pakhomov, D. Miklavcic and M.S. Marko, Eds.) pps. 371-383, CRC Press, 2010
Heller LC and Heller R. Gene Electrotransfer to Tumor, Electroporation in Science and Medicine, Kee, S., Lee, E., and Gehl, J.,Eds., Springer Science + Business Media, 2010
Kolb J. Generation of Ultrashort Pulse In: Advanced Electroporation Techniques in Biology in Medicine (A. G. Pakhomov, D. Miklavcic, and M.S. Markov, eds.), CRC Press, Taylor & Francis Group, Boca Raton, FL, 2010, pp. 341-352.
Pakhomov AG and Pakhomova ON. Nanopores: A distinct transmembrane passageway in electroporated cells. In: Advanced Electroporation Techniques in Biology in Medicine (A. G. Pakhomov, D. Miklavcic, and M.S. Markov, eds.), CRC Press, Taylor & Francis Group, Boca Raton, FL, 2010, pp. 177-194.
Pakhomov AG, Editor (jointly with D. Miklavcic and M.S. Markov) on "Advanced Electroporation Techniques in Biology and Medicine", CRC Press, Taylor & Francis Group, Boca Raton, FL, 2010.
Schoenbach KH. Bioelectric Effects of Intense Nanosecond Pulses In: Advanced Electroporation Techniques in Biology in Medicine (A. G. Pakhomov, D. Miklavcic, and M.S. Markov, eds.), CRC Press, Taylor & Francis Group, Boca Raton, FL, 2010, pp. 19-50.


Becker KH and Schoenbach KH, "High Pressure Microdischarges," chapter 17 in Low Temperature Plasmas. Fundamentals, Technologies and Techniques, R. Hippler, H. Kersten, M. Schmidt, and K.H. Schoenbach, eds., Wiley-VCH, Weinheim, Germany, 2008, pp. 463-494.
Schoenbach KH, Editor (jointly with R. Hippler, H. Kersten, and M. Schmidt) on a second edition of "Low Temperature Plasma Physics: Fundamental Aspects and Applications", Wiley-VCH, Weinheim, Germany, 2008