Core Facility Supervisor

PHONE: 757-683-2233

EMAIL: yjing@odu.edu

ADDRESS: IRP 2, 4211 Monarch Way, Norfolk, VA, 23508

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Education

Postdoctoral fellow, Eastern Virginia Medical School, 2007

Ph.D. Biomedical Sciences, Eastern Virginia Medical School, 2007

M.S. Statistics, Old Dominion University, 2005

Bachelor of Medicine (MD equivalent), Beijing Medical University, 1995

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Research Description

My research was focused on immunology and viral infectious disease. Specifically, I investigated NK cell alterations with aging, with particular interest on the upstream and downstream regulatory factors including pDCs, monocytes, and Th1 components, to extrapolate the cross talk and the potential cause for the aging-related reduction in NK cell function in response to influenza vaccination. I also conducted research on NKT cell subtype profile and the corresponding cytokine production in the context of aging. Furthermore, I studied gastroenteritis pathogens noroviruses and sapoviruses, exploring their seroprevalence, genetic classification and natural history of infection.

I am currently managing and supervising the interdisciplinary core lab at the ODU Frank Reidy Research Center for Bioelectrics (FRRCBE), providing need-based instrumentation and scientific support for faculty and students at ODU, neighboring institutions, and other research organizations in Hampton Roads.

Most relevant publications

1. Browning L, Miller C, Kuczma M, Pietrzak M, Jing Y, Rempala G, Muranski P, Ignatowicz L, Kraj P. Bone morphogenic proteins are immunoregulatory cytokines controlling Foxp3+ Treg cells. Cell Reports. 2020 Oct 6; 33(1):108219
2. Guo S, Jing Y, Burcus N, Lassiter B, Tanaz R, Heller R, Beebe S. Nano-pulse stimulation induces potent immune responses, eradicating local breast cancer while reducing distant metastases. International Journal of Cancer. 2018 Feb; 142(3):629-640
3. Jing Y, Shaheen E, Drake RR, Chen N, Gravenstein S, Deng Y. Aging is associated with a numerical and functional decline in plasmacytoid dencritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood. Hum Immunol. 2009 Oct; 70(10):777-84
4. Jing Y, Gravenstein S, Chaganty NR, Chen N, Lyerly KH, Joyce S, Deng Y. Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood. Exp Gerontol. 2007 Aug; 42(8):719-32
5. Jing Y, Qian Y, Huo Y, Wang L, Jiang X. Seroprevalence against Norwalk-like human caliciviruses in Beijing, China. Journal of Medical Virology. 2000 Jan; 60: 97-101

Awards and Honors

• Junior Investigator Scholarship Award at International Conference of Options for the Control of Influenza VI, 2007
• Postdoctoral Travel Award at Eastern Virginia Medical School Research Day, 2007
• Graduate Travel Award at Eastern Virginia Medical School Research Day, 2006