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Jennifer Poutsma

Jennifer Poutsma


Associate Professor
Chemistry & Biochemistry

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Education/Credentials


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  • Expertise

    Computational Chemistry
    Physical Organic Chemistry
  • Research Interests

    Dr. Poutsma’s group focuses on the application of computational chemistry to problems in organic, inorganic and biochemistry. Currently, the organic projects involve calculating the proton affinities of peptides, the mechanisms of mass spectrometry fragmentation and the mechanisms of peptide hydrogen/deuterium exchange. The goal of these projects is to expand our understanding of peptide fragmentation in order to improve the software used to predict protein sequence from mass spectrometry data. <br> <br>The inorganic project involves calculating the mechanisms of small aluminumoxide clusters with methane. The biochemistry projects focus on protein folding and are in conjunction with Dr. Lesley Greene of ODU.
  • 2015: Shining Star Recognition, Old Dominion University
  • 2011: Shining Star Award, Old Dominion University
  • 2009: Most Inspiring Faculty Award, Old Dominion University
  • 1998: NRSA Postdoctoral Fellowship, NIH
  • Contracts, Grants and Sponsored Research

    Poutsma, J. L. "Collaborative Research: Intrinsic Gas-phase Properties of Peptides: Thermochemistry, Fragmentation Mechanisms, H/D exchange and IRMPD Spectroscopy" $40,000. Federal. September 1, 2018 - August 31, 2021
    Poutsma, J. L. "Collaborative Research: Gas Phase Properties of Non-Protein Amino Acids; Thermochemistry, H/D Exchange, and Peptide Fragmentation Studies" $30,042. Federal. September 1, 2015 - August 31, 2018
    Poutsma, J. L. "Fragmentation Mechanisms, H/D exchange and IRMPD Spectroscopy of Non-Protein Amino Acids and Non-Protein Amino Acid-Containing Peptides" $45,654. Federal. September 1, 2015 - August 31, 2018
    Poutsma, J. L. "Investigations of Dihydrofolate Reductases Using Molecular Dynamics Simulations" $185,262. Federal. March, 2006 - February, 2008
    Poutsma, J. L. "Examination of the Mechanisms of the Schmidt and Modified-Schmidt Reactions" $80,000. Other. January, 2005 - August, 2007
    Poutsma, J. L. "Investigations of Biological and Organic Systems Using Computational Methods" $303,900. Other. October, 2005 - September, 2006
    Poutsma, J. L. "An Investigation of 2-Aminoethoxydiphenyl Borate and Analogs as Store-Operated Calcium Entry Channel Inhibitors" $10,000. State. January, 2003 - December, 2005
    Poutsma, J. L. "The Mechanism and Source of Stereoselectivity for a Reaction between a Hydroxy Alkyl Azide and a Substituted Cyclohexanone" $25,000. Other. September, 2001 - September, 2003
    Poutsma, J. L. "Investigation of the Loop Motions of Dihydrofalate Reductase" $5,000. Old Dominion University. June, 2001 - August, 2001