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Steven Pascal

Steven Pascal


PROFESSOR
Chemistry & Biochemistry

Contact Information


Education/Credentials


Web Link(s)



  • Expertise

    Chemistry
    NMR, Structural Biology, Structure Prediction
    Biology
    Viruses, Cancer, Structural Biology, Structure and Function
    Physics
    Biophysics,SAXS,Bioinformatics
  • Research Interests

    Combining NMR techniques with Small Angle X-ray Scattering (SAXS) and bioinformatics to determine protein and nucleic acid structure.
  • 2020: $433,00 NIH R21 award: Synthesis of enterovirus positive-strand RNAs: discovery of viral and host determinants of RNP complex formation
  • 2010: NZD 735,000 Royal Society Grant: Rhinoviral cloverleaf structure vis NMR/SAXS
  • 2008: NZD 83,000 Hort Research Grant: Biomed Applications of Plant
  • 2006: Distinguighed Teaching Award, Institute of Fundamental Sciences
  • 2006: Innovation & Excellence in Teaching Award: develop NMR visual for computer
  • 2006: Innovation and Excellence in Teaching award: develop NMR visual aids for computer
  • 2006: Member, Board of Directors, ANZMAG, Australia-NZ Magnetic Resonance Society
  • 2006: NZD 720,000 Royal Society Grant: Apoptosis/Cancer/Alzheimers via NMR
  • 2005: Distinguished Visiting Scholar NYSBC
  • 2005: NZD 75,000 Lottery Health Grant: Auto-tune/Match Module for NMR cryoprobe
  • 2004: NZD 75,000 Royal Society Grant: Picornaviral replication studies via NMR
  • 2004: Taught at EMBO mirror BioNMR workshop in Australia, G. Otting
  • 1998: USD 275,000 DOD Grant Award to study Prostate Cancer Molecules via NMR
  • 1997: Michael Kashs Lecturer - outstanding alumnus, Florida St. Molecular Biophys Program
  • 1996: Andrew Sass-Kortsak Award - Outstanding Fellow, Hospital for Sick Children
  • 1993: Doctoral Degree with Honours
  • 1993: Medical Research Council Postdoctoral Fellowship
  • 1991: University Fellowship
  • 1990: University Fellowship
  • 1989: University Fellowship
  • 1988: College Teaching Fellowship
  • 1988: Research Fellowship
  • 1988: University Fellowship
  • 1987: Research Fellowship
  • 1985: Graduation with Highest Distinction
  • 1985: Phi Beta Kappa
  • 1983: Board of Governors Scholarship
  • 1981: Board of Governors Scholarship
  • 1981: National Merit Finalist
  • 1981: Performance Scholarship, Music Department
  • 1981: Westinghouse Scholarship
  • Contracts, Grants and Sponsored Research

    Semler, B.; Pascal, S. "Synthesis of enterovirus positive-strand RNAs: discovery of viral and host determinants of RNP complex formation" $433,169. Federal. February, 2020 - January, 2023
    , "Biophysical characterization of full-length Par-4 tumor suppressor" $1,500. Old Dominion University. January, 2019 - May, 2019
    , "Par-4 tumor suppressor: structural changes that trigger the death of cancer cells" $10,000. Old Dominion University. January, 2018 - May, 2019
    , "Expression and Purification of HRV-14 proteins 3D & 3CD for in vitro studies" $1,500. Old Dominion University. January, 2014 - May, 2014
    , "Picornavirus RNA Template Synthesis, In Vitro Transcription and initial structural characterization" $1,500. Old Dominion University. January, 2013 - May, 2013
    , "Looking over a four-leaf clover: structural characterisation of a critical picornaviral RNA clover leaf and its interaction with a viral protein" $735,000. Foreign. January, 2009 - January, 2012
    , "The zipper, the butterfly and death: structural studies of an apoptosis-triggering protein-protein interaction linked to prostate cancer and neurodegenerative disease" $720,000. Federal. January, 2006 - January, 2010
    , "Biomedical Applications of Plant Genes" $83,000. January, 2008 - January, 2009
    , "Picornaviral Replication: Structures and Interactions of Two Key Viral Molecules" $630,000. Federal. January, 2004 - January, 2007
    , "Automated Tune and Match (ATM) Module for 700 MHz NMR Cryoprobe" $75,000. Federal. January, 2005 - December, 2005
    , "Structure and Interactions of a Protein Linked to Apoptosis Response in Prostate Tumors" $263,509. Federal. January, 1998 - January, 2001