Research

Photo of Robert Bruno and Patrick Sachs

Research areas include: Regenerative Medicine, Stem Cell Biology, Wound-healing, and Tissue Engineering; Drug and Gene Delivery; Cancer Biology and Therapy; Vascular Biology, Inflammation, and Cardiovascular Dysfunction; Novel Bioelectric Approaches to Cancer and Cardiovascular Therapies; Telomeres and Telomerase in Cancer, Aging, and Stem Cells.

Research Faculty

Professor & Chair Medical Diagnostic & Translational Sciences

Research Interests: Translational genomics of telomeres; telomere function and dysfunction in cancer, aging, and regenerative medicine; novel telomere-associated biomarkers.

Recent PublicationsNational Center for Biotechnology Information/PubMed

subtelomeres-labeled

telomeres-labeled

Associate Professor Medical Diagnostic & Translational Sciences

Research interests: stem cell biology, breast cancer tumor promotion, developmental biology, molecular mechanisms of huntington's disease, induced pluripotent stem cells.

Recent PublicationsNational Center for Biotechnology Information/PubMed

Laboratory websiteRobert D, Bruno, PhD

normal-breast-microenvironment-redirects

Normal breast microenvironment redirects MDA-MB-231 human breast cancer cells to adopt a normal mammary epithelial cell fate.

Professor Frank Reidy Research Center for Bioelectrics

Interim Executive Director & Sentara Endowed Chair, Frank Reidy Research Center for Bioelectrics

Research Interests: Vascular endothelium and vascular inflammation. Endothelial barrier function. Endothelial dysfunction in acute lung injury, ARDS and pulmonary hypertension. Anti-inflammatory actions of heat shock protein 90 inhibitors.

Recent PublicationsNational Center for Biotechnology Information/PubMed

protection-of-enfothelial-cells-by-Hsp90 inhibitors

Protection of endothelial cells by Hsp90 inhibitors.

Assoc Dean Of Education & Innovation College of Health Sciences

ASSISTANT PROFESSOR Medical Diagnostic & Translational Sciences

Associate Professor Medical Diagnostic & Translational Sciences

Research Interests: Techniques and technologies for elongating human lifespan, somatic cell reprograming, regenerative medicine, tissue engineering, stem cell biology, telomeres & telomerase.

Recent PublicationsNational Center for Biotechnology Information/PubMed

neuronal-progenitor

Neuronal progenitor cells differentiated from Huntington’s disease induced pluripotent stem cells. NPCs were probed for Beta-III tubulin expression (Green).