X. Nancy Xu

PROFESSOR
Chemistry & Biochemistry

Contact Information

CHEMISTRY BUILDING 4501 ELKHORN AVE
NORFOLK, VA 23529

Email: xhxu@odu.edu

Phone: 757-683-5698

Biography

Education/Credentials

Web Link(s)

Expertise

Chemistry

Analytical/Biochemistry/Bionanotechnology/Bionanomaterial/Biomedical Engineering

Nanotechnology

Bionanotechnology/Bionanomaterial/Biomedical Engineering

Biotechnology

Single Cell Analysis/Imaging

Real-time imaging

Single Live Cells/Embryos; Single Molecule/Nanoparticle Imaging
Research Interests

Dr. Xu has directed NSF and NIH funded nanoscale interdisciplinary research programs, aiming to develop and apply cutting-edge bionanotechnologies and ultrasensitive detection tools to address most challenging questions in biomedical and nano sciences. Her research program lies at the interface of Chemistry, Biology and Engineering as described at http://ww2.odu.edu/~xhxu/research.html

Articles

Songkiatisak, P., Ding, F., Cherukuri, P. K., and Xu, X. N. (2020). Size-dependent inhibitory effects of antibiotics nanocarriers on filamentation of E. Coli. Nanoscale Adv.

Cherukuri, P., SONGKIATISAK, P., Ding, F., and Xu, X. N. (2020). Antibiotic Drug Nanocarriers for Probing of Multidrug ABC Membrane Transporter of Bacillus subtilis. ACS Omega, 5, pp. 1625-1633.

Mathieu, K., Javed, W., Vallet, S., Lesterlin, C., Candusso, M., Ding, F., Xu, X. N., Ebel, C., Jault, J., and Orelle, C. (2019). Functionality of membrane proteins overexpressed and purified from E. coli is highly dependent upon the strain., 9, pp. 2654.

Ding, F., Cherukuri, P., Songkiatisak, P., Huang, T., Xu, X. N., and (2018). Size-dependent inhibitory effects of antibiotics drug nanocarriers against Pseudomonas aeruginosa. ACS Omega, 3, pp. 1231-1243.

Browning, L. M., Lee, K. J., Cherukuri, P. K., Huang, T., Songkiatisak, P., Warren, S., and Xu, X. N. (2018). Single Gold Nanoparticle Plasmonic Spectroscopy for Study of Chemical-Dependent Efflux Function of Single ABC Transporters of Single Live Bacillus subtilis Cells. Analyst, 143, pp. 1599-1608.

, Songkiatisak, P., Poudel, A., Phan, S., and Xu, X. N. (2017). Probing of effects of silver nanoparticles on single liver tumor cells. Papers of the American Chemical Society, 254 (1),

Browning, L. M., Lee, K. J., Nallathamby, . D., Cherukuri, P. K., Huang, T., Warren, S., and Xu, X. N. (2016). Single Nanoparticle Plasmonic Spectroscopy for Study of Charge-Dependent Efflux Function of Multidrug ABC Transporters of Single Live Bacillus subtilis Cells. The Journal of Physical Chemistry C, 120 (37), pp. 21007-21016.

Lee, K. J., Huang, T., Nallathamby, P. D., and Xu, X. N. (2015). Wavelength dependent specific plasmon resonance coupling of single silver nanoparticles with EGFP. Nanoscale, 7, pp. 17623–17630.

Ding, F., Lee, K. J., Vahedi-Faridi, A., Yoneyama, H., Osgood, C. J., and Xu, X. N. (2014). Design and study of the efflux function of the EGFP fused MexAB-OprM membrane transporter in Pseudomonas aeruginosa using fluorescence spectroscopy. Analyst, 139 (12), pp. 3088–3096.

Browning, L. M., Huang, T., and Xu, X. N. (2013). Real-time in vivo imaging of size-dependent transport and toxicity of gold nanoparticles in zebrafish embryos using single nanoparticle plasmonic spectroscopy. Interface Focus, 3 (3), pp. 20120098.

Browning, L. M., Lee, K. J., Nallathamby, P. D., and Xu, X. N. (2013). Silver nanoparticles incite size-and dose-dependent developmental phenotypes and nanotoxicity in zebrafish embryos. Chemical research in toxicology, 26 (10), pp. 1503–1513.

Lee, K. J., Browning, L. M., Nallathamby, P. D., Osgood, C. J., and Xu, X. N. (2013). Silver nanoparticles induce developmental stage-specific embryonic phenotypes in zebrafish. Nanoscale, 5 (23), pp. 11625–11636.

Lee, K. J., Browning, L. M., Nallathamby, P. D., and Xu, X. N. (2013). Study of charge-dependent transport and toxicity of peptide-functionalized silver nanoparticles using zebrafish embryos and single nanoparticle plasmonic spectroscopy. Chemical research in toxicology, 26 (6), pp. 904–917.

Xu, X. N., Wen, Z., and Brownlow, W. J. (2013). Ultrasensitive analysis of binding affinity of HIV receptor and neutralizing antibodies using solution-phase electrochemiluminescence assay. Journal of Electroanalytical Chemistry, 688, pp. 53–60.

Huang, T., Browning, L. M., and Xu, X. N. (2012). Far-field photostable optical nanoscopy (PHOTON) for real-time super-resolution single-molecular imaging of signaling pathways of single live cells. Nanoscale, 4 (9), pp. 2797–2812.

Huang, T., Cao, W., Elsayed-Ali, H., and Xu, X. N. (2012). High-throughput ultrasensitive characterization of chemical, structural and plasmonic properties of EBL-fabricated single silver nanoparticles. Nanoscale, 4 (2), pp. 380–385.

Lee, K. J., Browning, L. M., Nallathamby, P. D., Desai, T., Cherukuri, P. K., and Xu, X. N. (2012). In vivo quantitative study of sized-dependent transport and toxicity of single silver nanoparticles using zebrafish embryos. Chemical research in toxicology, 25 (5), pp. 1029–1046.

Lee, K. J., Nallathamby, P. D., Browning, L. M., Desai, T., Cherukuri, P. K., and Xu, X. N. (2012). Single nanoparticle spectroscopy for real-time in vivo quantitative analysis of transport and toxicity of single nanoparticles in single embryos. Analyst, 137 (13), pp. 2973–2986.

Ding, F., Lee, K. J., Vahedi-Faridi, A., Huang, T., and Xu, X. N. (2011). Design and probing of efflux functions of EGFP fused ABC membrane transporters in live cells using fluorescence spectroscopy. Analytical and bioanalytical chemistry, 400 (1), pp. 223–235.

Cao, W., Huang, T., Xu, X. N., and Elsayed-Ali, H. (2011). Localized surface plasmon resonance of single silver nanoparticles studied by dark-field optical microscopy and spectroscopy. Journal of applied physics, 109 (3), pp. 034310.

Huang, T., and Xu, X. N. (2011). Multicolored nanometre-resolution mapping of single protein–ligand binding complexes using far-field photostable optical nanoscopy (PHOTON). Nanoscale, 3 (9), pp. 3567–3572.

Nallathamby, P. D., Huang, T., and Xu, X. N. (2010). Design and characterization of optical nanorulers of single nanoparticles using optical microscopy and spectroscopy. Nanoscale, 2 (9), pp. 1715–1722.

Browning, L. M., and Xu, X. N. (2010). Electric pulses to prepare feeder cells for sustaining and culturing of undifferentiated embryonic stem cells. Biotechnology journal, 5 (6), pp. 588–595.

Lee, K. J., Browning, L. M., Huang, T., Ding, F., Nallathamby, P. D., and Xu, X. N. (2010). Probing of multidrug ABC membrane transporters of single living cells using single plasmonic nanoparticle optical probes. Analytical and bioanalytical chemistry, 397 (8), pp. 3317–3328.

Nallathamby, P. D., and Xu, X. N. (2010). Study of cytotoxic and therapeutic effects of stable and purified silver nanoparticles on tumor cells. Nanoscale, 2 (6), pp. 942–952.

Huang, T., and Xu, X. N. (2010). Synthesis and characterization of tunable rainbow colored colloidal silver nanoparticles using single-nanoparticle plasmonic microscopy and spectroscopy. Journal of materials chemistry, 20 (44), pp. 9867–9876.

Song, Y., Nallathamby, P. D., Huang, T., Elsayed-Ali, H., and Xu, X. N. (2009). Correlation and Characterization of Three-Dimensional Morphologically Dependent Localized Surface Plasmon Resonance Spectra of Single Silver Nanoparticles Using Dark-Field Optical Microscopy and Spectroscopy and Atomic Force Microscopy. The Journal of Physical Chemistry C, 114 (1), pp. 74–81.

Browning, L. M., Lee, K. J., Huang, T., Nallathamby, P. D., Lowman, J. E., and Xu, X. N. (2009). Random walk of single gold nanoparticles in zebrafish embryos leading to stochastic toxic effects on embryonic developments. Nanoscale, 1 (1), pp. 138–152.

Xu, H., Nallathamby, P. D., and Xu, X. N. (2009). Real-time imaging and tuning subcellular structures and membrane transport kinetics of single live cells at nanosecond regime. The Journal of Physical Chemistry B, 113 (43), pp. 14393–14404.

Nallathamby, P. D., Lee, K. J., and Xu, X. N. (2008). Design of stable and uniform single nanoparticle photonics for in vivo dynamics imaging of nanoenvironments of zebrafish embryonic fluids. Acs Nano, 2 (7), pp. 1371–1380.

Huang, T., Nallathamby, P. D., and Xu, X. N. (2008). Photostable single-molecule nanoparticle optical biosensors for real-time sensing of single cytokine molecules and their binding reactions. Journal of the American Chemical Society, 130 (50), pp. 17095–17105.

Lee, K. J., Nallathamby, P. D., Browning, L. M., Osgood, C. J., and Xu, X. N. (2007). ACS Nano 2007, 1, 133–143. CrossRef| PubMed| CAS| Web of Science® Times Cited, 45,

Huang, T., Nallathamby, P. D., Gillet, D., and Xu, X. N. (2007). Design and synthesis of single-nanoparticle optical biosensors for imaging and characterization of single receptor molecules on single living cells. Analytical chemistry, 79 (20), pp. 7708–7718.

Xu, X. N., and Zu, Y. (2007). Electrochemiluminescence detection in bioanalysis. Chemical Analysis-New York-Interscience then John Wiley-, 172, pp. 235.

Lee, K. J., Nallathamby, P. D., Browning, L. M., Osgood, C. J., and Xu, X. N. (2007). In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryos. ACS nano, 1 (2), pp. 133–143.

Xu, X. N., Song, Y., and Nallathamby, P. (2007). Probing membrane transport of single live cells using single-molecule detection and single nanoparticle assay. Chemical Analysis-New York-Interscience then John Wiley-, 172, pp. 41.

Xu, X. N., and Patel, R. (2005). Imaging and assembly of nanoparticles in biological systems. Handbook of nanostructured biomaterials and their applications in nanobiotechnology, 1, pp. 435–456.

Xu, X. N., Brownlow, W. J., Kyriacou, S. V., Wan, Q., and Viola, J. J. (2004). Real-time probing of membrane transport in living microbial cells using single nanoparticle optics and living cell imaging. Biochemistry, 43 (32), pp. 10400–10413.

Steel, C., Wan, Q., and Xu, X. N. (2004). Single live cell imaging of chromosomes in chloramphenicol-induced filamentous Pseudomonas aeruginosa. Biochemistry, 43 (1), pp. 175–182.

Xu, X. N., Huang, S., Brownlow, W., Salaita, K., and Jeffers, R. B. (2004). Size and Temperature Dependence of Surface Plasmon Absorption of Gold Nanoparticles Induced by Tris (2, 2 ‘-bipyridine) ruthenium (II). The Journal of Physical Chemistry B, 108 (40), pp. 15543–15551.

Kyriacou, S. V., Brownlow, W. J., and Xu, X. N. (2004). Using nanoparticle optics assay for direct observation of the function of antimicrobial agents in single live bacterial cells. Biochemistry, 43 (1), pp. 140–147.

Xu, X. N., Wan, Q., Kyriacou, S. V., Brownlow, W. J., and Nowak, M. E. (2003). Direct observation of substrate induction of resistance mechanism in Pseudomonas aeruginosa using single live cell imaging. Biochemical and biophysical research communications, 305 (4), pp. 941–949.

Xu, X. N., Brownlow, W., Huang, S., and Chen, J. (2003). Real-time measurements of single membrane pump efficiency of single living Pseudomonas aeruginosa cells using fluorescence microscopy and spectroscopy. Biochem. Biophys. Res. Commun, 305, pp. 79–86.

Xu, X. N., Brownlow, W., Huang, S., and Chen, J. (2003). Single-molecule detection of efflux pump machinery in Pseudomonas aeruginosa. Biochem. Biophys. Res. Commun., 305, pp. 79.

Xu, X. N., Chen, J., Jeffers, R. B., and Kyriacou, S. (2002). Direct measurement of sizes and dynamics of single living membrane transporters using nanooptics. Nano Letters, 2 (3), pp. 175–182.

Kyriacou, S. V., Nowak, M. E., Brownlow, W. J., and Xu, X. N. (2002). Single live cell imaging for real-time monitoring of resistance mechanism in Pseudomonas aeruginosa. Journal of biomedical optics, 7 (4), pp. 576–586.

Xu, X. N., Jeffers, R. B., Gao, J., and Logan, B. (2001). Novel solution-phase immunoassays for molecular analysis of tumor markers. Analyst, 126 (8), pp. 1285–1292.

Xu, X. N., and Yeung, E. S. (1998). Long-range electrostatic trapping of single-protein molecules at a liquid-solid interface. Science, 281 (5383), pp. 1650–1653.

Xu, X. N., and Yeung, E. S. (1997). Direct measurement of single-molecule diffusion and photodecomposition in free solution. Science, 275 (5303), pp. 1106–1109.

Xu, X. N., Shreder, K., Iverson, B. L., and Bard, A. J. (1996). Generation by Electron Transfer of an Emitting State Not Observed by Photoexcitation in a Linked Ru (bpy) 32+- Methyl Viologen. Journal of the American Chemical Society, 118 (15), pp. 3656–3660.

Xu, X. N., and Bard, A. J. (1995). Immobilization and hybridization of DNA on an aluminum (III) alkanebisphosphonate thin film with electrogenerated chemiluminescent detection. Journal of the American chemical society, 117 (9), pp. 2627–2631.

Xu, X. N., and Bard, A. J. (1994). Electrogenerated chemiluminescence. 55. Emission from adsorbed Ru (bpy) 32+ on graphite, platinum, and gold. Langmuir, 10 (7), pp. 2409–2414.

Xu, X. N., Yang, H. C., Mallouk, T. E., and Bard, A. J. (1994). Immobilization of DNA on an aluminum (III) alkanebisphosphonate thin film with electrogenerated chemiluminescent detection. Journal of the American chemical society, 116 (18), pp. 8386–8387.

Xu, X. N., and Hussey, C. L. (1993). The Electrochemistry of Tin in the Aluminum Chloride-1-methyl-3-ethylimidazolium Chloride Molten Salt. Journal of The Electrochemical Society, 140 (3), pp. 618–626.

Xu, X. N. (1992). Electrodeposition of metals from room-temperature chloroaluminate molten salts. Proc. of Electrochem. Soc., 16, pp. 445.

Xu, X. N., and Hussey, C. L. (1992). Electrodeposition of Silver on Metallic and Nonmetallic Electrodes from the Acidic Aluminum Chloride-1-Methyl-3-Ethylimidazolium Chloride Molten Salt. Journal of The Electrochemical Society, 139 (5), pp. 1295–1300.

Xu, X. N., and Hussey, C. L. (1992). The Electrochemistry of Gold at Glassy Carbon in the Basic Aluminum Chloride-1-Methyl-3-ethylimidazolium Chloride Molten Salt. Journal of The Electrochemical Society, 139 (11), pp. 3103–3108.

Hussey, C. L., and Xu, X. N. (1991). Electrodissolution and electrodeposition of lead in an acidic room temperature chloroaluminate molten salt. Journal of The Electrochemical Society, 138 (7), pp. 1886–1890.
Book Chapters

Xu, X. N. (2017). Far-Field Photostable Optical Nanoscopy (PHOTON).Encyclopedia of Spectroscopy and Spectrometry (pp. 566–570). Oxford: Elsevier.

Xu, X. N. (2007). Outlooks of ultrasensitive detection in bioanalysis.New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis (pp. 295–299). Wiley.

Xu, X. N., Song, Y., and Nallathamby, P. (2007). Probing membrane transport of single live cells using single molecule detection and single nanoparticle assay.New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis (pp. Chapter 3, 41-70). Wiley.

Xu, X., and Patel, R. (2005). Imaging and assembly of nanoparticles in biological systems.Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology (pp. Chapter 13, 435-456). American Scientific Publisher.

Xu, X. N., and Patel, R. N. (2004). Nanoparticles for Live-Cell Dynamics.Encyclopedia of Nanoscience and Nanotechnology (pp. 181–192). American Scientific Publishers.
Presentations

Xu, X. (August, 2019). New Nano Tools for Real-time Single Molecule Imaging of Single Live Cells: From Fundamental Discoveries to biomedical Applications Oral Presentation presented at 258th ACS National Meeting 2019 San Diego, CA (invited).

Xu, X., Songkiatisak, P., Cherukuri, P., Raut, K., and Richardson, R. (April, 2019). Single nanoparticle plasmonic spectroscopy for biomedical applications: from diagnosis to therapy Oral Presentation presented at 258th ACS National Meeting 2019 San Diego, CA (invited).

Xu, X. (March, 2019). Real-time probing of cytotoxic and therapeutic effects of single nanoparticles on single tumor cells Oral Presentation presented at 257th ACS National Meeting 2019 Orlando, FL (invited).

Xu, X., Songkiatisak, P., Cherukuri, P., and Raut, K. (February, 2019). Single Nanoparticle Optical Biosensors for Real-time, Single-Molecule and Super-Resolution Imaging of Single Live Cells Oral Presentation presented at Pittcon 2019 Philadelphia, PA.

Xu, X. (February, 2019). Single nanoparticle spectroscopic imaging for probing of multidrug membrane transporters of single live cells Oral Presentation presented at Pittcon 2019 Philadelphia, PA..

Xu, X., Songkiatisak, P., Cherukuri, P., Ding, F., and Huang, T. (August, 2018). Multifunctional size-dependent drug nanocarriers for probing multidrug membrane transporters of single live cells Oral Presentation presented at 256th ACS National Meeting 2018 Boston, MA (invited).

Xu, X., Songkiatisak, P., and Cherukuri, P. (August, 2018). Photostable optical nanoscopy (PHOTON) for cancer research Oral Presentation presented at 256th ACS National Meeting 2018 Boston, MA (invited).

Xu, X., Johnson, M., Cherukuri, P., Songkiatisak, P., and Raut, K. (April, 2018). BRAIN-EAGER: New tools for real-time in vivo imaging of single neuron-neuron communication during embryonic development Oral Presentation presented at 4th BRAIN Initiative Investigators Meeting 2018 Baltimore, MD (invited).

Xu, X. (November 30, 2017). New Imaging Tools for Following Single Live Cells: From Fundamental Discoveries to Biomedical Applications Lecture presented at Seminar Old Dominion University (Invited).

Xu, X. N., Johnson, M., Cherukuri, P., and Songkiatisak, P. (November 10, 2017). Photostable nanosensors for real-time and single molecular imaging and tracking of neurotransmitters in situ presented at Neuroscience 2017 Washington DC.

Xu, X. (October 24, 2017). Chair Symposium "Translation To Diagnostic and Therapeutic Applications" Keynote/Plenary Address presented at 3rd Annaul Next Generation Sequencing & Clinical Diagnostics Congress & Single Cell Analysis USA Congress Boston, MA (Invited).

Xu, X. (October 24, 2017). New nano tools for real-time single-molecular sensing and imaging of single live cells Oral Presentation presented at 3rd Annaul Next Generation Sequencing & Clinical Diagnostics Congress & Single Cell Analysis USA Congress 3rd Annaul Next Generation Sequencing & Clinical Diagnostics Congress & Single Cell Analysis USA Congress, Boston, MA (Invited).

Songkiatisak, P., Cherukuri, P., and Xu, X. N. (August 21, 2017). Real-time imaging and sensing of single cancer stem cells Oral Presentation presented at 254th ACS National Meeting 2017 254th ACS National Meeting 2017, Washington DC.

Johnson, M., and Xu, X. N. (August 21, 2017). Real-time in vivo monitoring of single neuron-neuron communication Oral Presentation presented at 254th ACS National Meeting 2017 Washington DC.

Xu, X. (August 20, 2017). Organizer/Chair: Invited Symposium "Nanotechnology & Single Cell Analysis in Biology and Medicine" Oral Presentation presented at 254th ACS National Meeting 2017 Washington DC (Invited).

Songkiatisak, P., Cherukuri, P., and Xu, X. (August 20, 2017). Probing of effects of silver nanoparticles on single liver tumor cells Oral Presentation presented at 254th ACS National Meeting 2017 Washington DC.

Xu, X., Songkiatisak, P., and Cherukuri, P. (August 20, 2017). Photostable optical nanoscopy (PHOTON) for following single live cells: From fundamental discoveries to biomedical applications Oral Presentation presented at 254th ACS National Meeting 2017, Washington DC Washington DC (Invited).

Xu, X. (June 29, 2017). Photostable multiplexing nanoassays for real-time molecular imaging of single live cells presented at 5th Annual Single Cell Analysis Investigator Meeting IH Campus, Bethesda, MD (Invited).

Xu, X., Cherukuri, P., Songkiatisak, P., and Phan, S. (March 09, 2017). New nano tools for real-time imaging of single cancer stem cells Oral Presentation presented at Pittcon’2017 Chicago, IL (Invited).

Xu, X. (March 09, 2017). Organizer/Chair: Invited Symposium "Impacts of Single Cell Analysis on Biology and Medicine" Oral Presentation presented at Pittcon’2017 Chicago, IL.

Xu, X. (2013). Oral Presentation presented at http://www.odu.edu/sci/xu/publications.html United States.

Xu, X. N. (2009). Design of Photostable Nanoparticle Optics and Biosensors for Molecular Imaging of Single Living Cells Virginia Commonwealth University, Richmond, VA (Invited).

Xu, X. N. (2009). Design of Photostable Nanoparticles for Molecular Imaging of Single Living Cells and Embryos Brown University (Invited).

Xu, X. N. (2009). Design of Photostable Plasmonic Nanoparticle Probes and Biosensors for Molecular Imaging of Single Living Cells Clemson University (Invited).

Xu, X. N. (2008). New Frontiers in Nanoscience and Nanotechnology: Design of Biocompatible Single Nanoparticle Optics for Imagine Single Living Cells Xiamen University (Invited).

Xu, X. N. (2007). Design of Biocompatible Single Nanoparticle Optics for Imaging Single Living Cells Rice University (Invited).

Xu, X. N. (2007). Design of Single Nanoparticle Biosensors for Real-time Imaging of Single Living Cells University of Maryland at College Park (Invited).

Xu, X. N. (2007). Design of Single Nanoparticle Optics for Molecular Imaging of Single Living Cells Rensselaer Polytechnic Institute (Invited).

Xu, X. N. (2007). Design of Single Nanoparticle Photonics and Biosensors for Real-time Molecular Analysis of Single Living Cells.

Xu, X. N. (2007). Design of Single Nanoparticle Photonics and Senors for Real-time Probing of Single Living Cells and Embyroys University of Washington, Seattle (Invited).

Xu, X. N. (2007). New Frontiers in Nanobiotechnology: Design of Biocompatible Nanoparticles for Real-Time Molecular Imaging of Single Living Cells Hampton University, Hampton, VA (Invited).

Xu, X. N. (2006). Design of Biocompatible Single Nanoparticle Optics for Real-Time Molecular Imaging of Living Cellular Function Northeastern University (Invited).

Xu, X. N. (2006). Design of Biocompatible Single Nanoparticle Optics for Real-Time Molecular Imaging of Membrane Transport in Single Living Cells University of Illinois at Urbana-Champaign (Invited).

Xu, X. N. (2006). Design of single nanoparticle optics for probing living cellular function National Institute of Aerospace (Invited).

Xu, X. N. (2005). Frontiers in Nanoscience and Nanotechnology, NIRT Lecture Series-2005: Design of Single Nanoparticle Optics for Probing Living Cellular Membrane Transport Lecture presented at 1st Annual Public Lecture of NIRT Program at ODU Old Dominion University.

Xu, X. N. (2005). Design of single nanoparticle optics for probing living cellular cellular membrane transport University of Illinois at Urbana-Champaign (Invited).

2020: 2020 Reign on Faculty Recognition Award , Division of Student Engagement and Enrollment Services
2020: 2020 AAAS Mentor Award, American Association for The Advancement of Science (AAAS)
2019: Expert Panelist for 2019 NIH BRAIN Initiatives: Chemogenetic Innovations, NIH
2019: 2019 ACS Division of Analytical Chemistry Roland F. Hirsch Award , American Chemical Society (ACS)
2019: Member of Advisory Board Frank Reidy Research Center for Bioelectrics
2018: John R. Broderick University Diversity Champion Award , Old Dominion University
2018: Shining Star Recognition from ODU Division of Student Engagement & Enrollment Services , Old Dominion University
2018: Appointed Group coordinator/leader of the Virginia Neuroscience Initiative, commonwealth of Virginia
2018: Faculty Proposal Preparation Program (FP3) Award, Old Dominion University
2018: Provost Certificate of Excellence in Promoting Undergraduate Research , Old Dominion University
2018: Re-elected Alternative Councilor and Member of Executive Committee, ACS Analytical Chemistry Division (2016-2021) , American Chemical Society
2018: Appointed to ACS joint Board-Council Committee on Publications, American Chemical Society
2016: Elected Alternative Councilor & Member of Executive Committee, ACS Analytical Chemistry Division , American Chemical Society
2015: Phase-I Finalist of Single Cell Analysis Challenge, NIH Common Fund, NIH Office of Director , NIH
2015: Shining Star Recongnition, ODU Division of Student Engagement and Enrollment Services
2014: NSF BRAIN Initiative EAGER Awardee, NSF
2014: Reviewer (jury) of Spectrochemical Analysis Award of ACS Division of Analytical Chemistry, 2012-2014, American Chemical Society
2013: Reviewer (jury) of Spectrochemical Analysis Award of ACS Division of Analytical Chemistry, American Chemical Society
2012: Certificate of Excellence in promoting Undergraduate Research, ODU
2012: Reviewer (jury) of Spectrochemical Analysis Award of ACS Division of Analytical Chemistry, 2012-2014, American Chemical Society
2011: Certificate of Appreciation from ACS for valuable contribution and dedicated service in the peer-review of manuscripts subscribed to ACS journal , American Chemical Society
2011: Fellow of the American Association for the Advancement of Science (AAAS), AAAS
2010: 2010 ODU Faculty Research Achievement Award, Old Dominion University
2009: 2009 Distinguished Research Award of College of Sciences at ODU, Old Dominion University
2008: 2008 Nanotech Briefs Nano 50 Trademark Innovator Award, Nanotech Briefs
2007: 2007 Nanotech Briefs Nano 50 Trademark Awards in Technology, Nanotech Briefs
2007: Student-selected Most Inspiring Faculty Member, College of Sciences, ODU, Old Dominion University
2005: Student-selected Most Inspiring Faculty Member, College of Sciences, ODU, Old Dominion University
2005: Student-selected seminar speaker (one per year), University of illinois at Urbana-Champaign, University of illinois at Urbana-Champaign

Contracts, Grants and Sponsored Research

Xu, X. "New Tools for Real-Time Probing of Multidrug ABC Transporters" $1,885,604. Federal. September 1, 2021 - August 31, 2026

Xu, X. N. "New Photostable Nanoprobes for Real-time Imaging of Single Live Cells" $465,000. Federal. April, 2016 - April, 2021

Xu, X. "NSF BRAIN EAGER: New Tools for Real-Time Imaging of Molecular-Resolution Connectomics of Synapses" $359,307. Federal. September, 2014 - August, 2020

Xu, X. "GRA Supplement " $34,935. Federal. June, 2014 - August, 2020

Xu, X. "REU Supplement" $24,000. Federal. June, 2014 - August, 2020

Xu, X. "Photostable Multiplexing NanoAssays for Real-Time Study of Embryonic Stem Cells" $420,750. Federal. September, 2015 - July, 2020

Xu, X. "Research Supplement to Promote Diversity in Health-Related Research" $89,616. Federal. August 01, 2017 - March 31, 2020

Xu, X. N.; Osgood, C. J. "New Photostable Nanoprobes For Real-Time Imaging of Single Live Cells" $372,000. Federal. April 1, 2016 - March 31, 2020

Xu, X. "Catalyzing New International Collaborations (CNIC) Supplement" $75,000. Federal. 2014 - 2018

Xu, X. N.; Osgood, C. J. "Photostable Multiplexing Nanoassays For Real-Time Study of Embryonic STEM Cells" $184,062. Federal. August 1, 2016 - July 30, 2018

Xu, X. "Catalyzing New International Collaborations (CNIC) Supplement" $100,000. Federal. 2013 - May, 2018

Xu, X. "NSF/GRA Supplement (CBET 0507036)" $40,738. Federal. September, 2009 - May 31, 2018

Xu, X. "NIRT: Design of Biocompatible Nanoparticles for Probing Living Cellular Functions and Their Potential Environmental Impacts" $1,256,494. Federal. June 01, 2005 - May 31, 2018

Xu, X. "Nanoassay for Real-time Molecular Probing ABC Transporter" $1,246,431. Federal. May, 2006 - May, 2014

Xu, X. "Nanoassay for study of multidrug resistance in bacteria" $84,910. Federal. July, 2006 - June, 2013

Xu, X. "Nanoassay for Real-time Molecular Probing ABC Transporter" $430,387. Federal. October, 2009 - September, 2012

Xu, X. "NSF/GRA Supplement (CBET 0507036)" $35,486. Federal. August, 2008 - May 31, 2009

Xu, X. "NSF/GRA Supplement (CBET 0507036)" $34,176. Federal. July, 2007 - May 31, 2009

Xu, X. "NSF/GRA Supplement for NIRT (BES 0631940)" $33,081. Federal. August, 2006 - May 31, 2009

Xu, X. "NSF/GRA Research Supplement (BES 0542582)" $100,000. Federal. August, 2005 - May 31, 2009

Xu, X. "NSF/GRA Supplement (BES 0541661)" $32,346. Federal. July, 2005 - May 31, 2009

Xu, X. "NSF/RET Supplement for NIRT (BES 0507036)" $10,000. Federal. July, 2005 - May 31, 2009

Xu, X. "NSF (MRI: DMR 0420304)" $119,000. Federal. July, 2004 - June, 2007

Xu, X.; Joshi, R.; Schoenbach, K.; Beebe, S.; Weaver, J.; Roti-Roti, J.; Meltz, M.; Mohan, N.; Weintraub, S.; Hagness, S.; Booske, J. "MURI-02: Subcellular Responses to Narrowbound and Wideband Radiofrequency Radiation" $5,000,000. Federal. June, 2002 - May, 2007

Xu, X. "Real-Time Molecular Study of Bystander Effect Using Living Cell Imaging and Nanoparticle Optics" $236,512. Federal. September, 2003 - August, 2006

Xu, X. "Real-Time Single-Molecule Chemical Microscopy" $214,500. Federal. April, 2000 - March, 2004
Intellectual Property

Nanoparticle Biosensors

Patent/Copyright: Patent

Patent Nationality: United States

Inventors:
Xu, X.
Huang, T.
Nallathamby, P.

New Green Methods for Culture of Embryonic Stem Cells

Patent/Copyright: Patent

Patent Nationality: United States

Inventors:
Xu, X.
Browning, L.

Stable Nanoparticles, Nanoparticle-Based Imaging Systems, Nanoparticle-Based Assays

Patent/Copyright: Patent

Patent Nationality: United States

Inventors:
Xu, X.
Nallathamby, P.
Lee, K.

Metallic nanoparticles for inhibition of bacterium growth

Patent/Copyright: Patent

Patent Nationality: United States

Inventors:
Xu, X.
Jeffers, R.
Kyriacou, S.

Biosensor for and Method of Electrogenerated Chemiluminescent Detection of Nucleic Acid Adsorbed to a Solid Surface

Patent/Copyright: Patent

Patent Nationality: Patent Cooperation Treaty

Cooperation Treaty: Canadian Patent Application No. 2198489, Australian Patent No. 703344, World Intellectual Property Organization No. W09606946A, European Patent Application No. EP00777741A1

Inventors:
Xu, X. N.
Bard, A. J.

Old Dominion University

Idea Fusion

X. Nancy Xu

X. Nancy Xu

Contact Information

Organizational Chart

Biography

Education/Credentials

Web Link(s)

Expertise

Research Interests

Articles

Book Chapters

Presentations

Contracts, Grants and Sponsored Research

Intellectual Property